While an M3 Ultra Mac Studio was used for the computing tasks, and inspired DIYers should “budget 100GB free per run” of the sequencer, they suggest “a recent Apple Silicon Mac (M3 or later, with enough RAM) is sufficient.” However, an Nvidia DGX Spark could do the processing up to 5x faster.
It isn’t revealed what the intrepid DIYer learned from their own process – perhaps it is too personal, but they insist that “the things you can do with this [mapped genome] file are vast.” One suggestion for potential followers is to run results through DeepMind's AlphaGenome. The DIYer even ends by saying they’re happy to help fellow genome-curious folks, bringing their MinION along, depending on location. A contact form is provided to reach out.
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Mark Tyson is a news editor at Tom's Hardware. He enjoys covering the full breadth of PC tech; from business and semiconductor design to products approaching the edge of reason. ","collapsible":{"enabled":true,"maxHeight":250,"readMoreText":"Read more","readLessText":"Read less"}}), "https://slice.vanilla.futurecdn.net/13-4-20/js/authorBio.js"); } else { console.error('%c FTE ','background: #9306F9; color: #ffffff','no lazy slice hydration function available'); } Mark Tyson Social Links Navigation News Editor Mark Tyson is a news editor at Tom's Hardware. He enjoys covering the full breadth of PC tech; from business and semiconductor design to products approaching the edge of reason.
scottsoapbox So how much is professional sequencing? 5 grand isn’t cheap for less accurate measurement. Reply
mikettt scottsoapbox said: So how much is professional sequencing? 5 grand isn’t cheap for less accurate measurement. Whole Genome sequencing (WGS) is $300 from Tellmegen. This is interesting but he did this for fun, not to save money. Reply
ackza Even if fair it's still cool and should still be funded cuz I bet u can still do it for real for like $30k Reply
Hooda Thunkett scottsoapbox said: So how much is professional sequencing? 5 grand isn’t cheap for less accurate measurement. True, but then someone else has your most personal data. Assuming you want to know something specific about your genes, it might be worth $5k to keep it out of corporate hands. Reply
Dalek-Kaan What was that movie ? Gataca ? laws passed to protect people from exactly this kind of thing mean nothing when a simple search could turn up bio data about your FUTURE health …and large corporations would do it without any doubt… Reply
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Reference reading
- https://www.tomshardware.com/tech-industry/artificial-intelligence/SPONSORED_LINK_URL
- https://www.tomshardware.com/tech-industry/artificial-intelligence/biohacker-claims-to-have-sequenced-their-own-genome-at-the-kitchen-table-with-m3-ultra-mac-studio-claude-and-a-usd3-200-sequencer-diy-project-requires-100gb-of-data-storage-per-run-oodles-of-ram#main
- https://www.tomshardware.com
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